Motorists are advised to plan ahead for this weekends Sutherland 2 Surf.
More than 8,000 people are expected to either run or walk in the annual 11km event on Sunday.
Roads will start closing from 5:30am, with major roads including the Kingsway closing from 7:30am.
Motorists will still be able to cross the Kingsway at certain spots but are encouraged to use The Boulevarde, Captain Cook Drive or President Avenue instead.
Other major road closures include Acacia Road, Taren Point Road and Port Hacking Road.
Roads will progressively reopen from 8:50am as participants make their way along the course.
All roads are expected to be open 10:30am.
Due to the road closures, Route 477 buses will be diverted.
Passengers should board services from a temporary stop on Kiora Road before the Kingsway.
Special event buses will also run to the start line at Sutherland from Cronulla High School between 6:30am and 7:15am.
After the race presentation, buses will run back to Cronulla High School, with the last bus leaving at 11am.
Trains run frequently to Sutherland on the T4 Eastern Suburbs and Illawarra Line.