Cronulla will be without Wade Graham for up to a month after the Sharks forward suffered a hamstring injury in the State of Origin decider on Wednesday night.
Graham played just 17 minutes off the bench for NSW before withdrawing with a hamstring strain in the second half.
The Blues went on to win an epic match 26-20 in the dying seconds to retain the Origin shield for the first time since 2005.
Graham had played just 86 minutes of NRL football this season after returning from a nine-month layoff following his knee reconstruction, before being chosen in the NSW side for game two in Perth.
He retained his place in the Blues side for game three, only to suffer another frustrating injury.
Scans on Thursday revealed Graham had suffered a grade two hamstring strain.
Cronulla said they expected Graham to miss between three and four weeks with the problem.
Sharks coach John Morris is likely to turn to Kurt Capewell to slot in for Graham when Cronulla face the Storm in Melbourne on Saturday night.
The Sharks, who are on a three-match losing streak, will also be without captain Paul Gallen with a gluteal strain.
