The Sharks gave prop Aaron Woods a memorable 200th NRL game celebration with a 36-26 come from behind win over Brisbane last week but know this week it will be different.
Cronulla had centre Jackson Ferris and half Braydon Trindall on debut and coach John Morris said It was one of the most courageous wins that he had been a part of.
"We came up here without Josh Dugan, Jesse Ramien, Chad Townsend, Matt Moylan and Andrew Fifita and lost young Jacko [Jackson Ferris] during the game so I thought it was a marvellous effort to come from behind.
"There were only three guys in that team who had played over 50 games - Woods, Shaun [Johnson] and Wade [Graham] - so they grabbed the team by the scruff of the neck and Woodsy led all that."
Tries to Sione Katoa, Connor Tracey and Braden Hamlin-Uele clinched the win for Cronulla and handed the Broncos a ninth loss in their past 10 games.
Adding to the injury list Sharks debutant, Jackson Ferris is also set to be suspended for a shoulder charge on Brisbane's Herbie Farnworth after his first game in the top grade, with four other players also charged from Friday night's two games.
The Sharks are now climbing the NRL ladder, in sixth position on 14 points, having won six out of the last seven.
Cronulla is hopeful of having the experienced Jesse Ramien and Josh Dugan back next week from hamstring injuries to face the Eels in round 13 at Jubilee Oval on Sunday afternoon with Coach Morris saying that Matt Moylan was also a good chance to play.